Dostarlimab Lifesaving Drug: A Review

Authors

  • Madhuri S. Nandgave, Neha D. Upare, Triveni Muneshwar, Mr. Upadesh B. Lade Chhatrapati Shivaji College of Pharmacy, Deori, Dist Gondia (441901)

Keywords:

Anti PD-1, Dostarlimab, Cancer Therapy, Monoclonal Antibody, Endometrial Cancer and Rectal Cancer.

Abstract

Dostarlimab, sold under the brand name Jemperli, is a monoclonal antibody used as an anti-cancer medication for the treatment of endometrial cancer. Dostarlimab is a programmed death receptor-1 (PD-1)–blocking monoclonal antibody Dostarlimab, according to doctors at New York's Memorial Sloan Kettering Cancer Center, can entirely remove the disease in persons with a specific type of rectal cancer. Because we are observing an alarming surge in rectal cancer among Malayalee youth, the 'Dostarlimab' treatment will be of essential importance in research. .it Regulation of PD-1 ligands occurs in some tumors, and signaling through this pathway can contribute to inhibition of active T-cell immune surveillance of tumors. Dostarlimab-gxly is a humanized monoclonal antibody of the IgG4 isotype that binds to the PD-1 receptor and blocks its interaction with PD-L1 and PD-L2, releasing PD-1 pathway-mediated inhibition of the immune response, including the anti-tumor immune response. Hence dostralimb it is help to cure cancer patients.

Published

2023-07-14

How to Cite

Madhuri S. Nandgave, Neha D. Upare, Triveni Muneshwar, Mr. Upadesh B. Lade. (2023). Dostarlimab Lifesaving Drug: A Review. International Journal of New Media Studies: International Peer Reviewed Scholarly Indexed Journal, 10(2), 48–51. Retrieved from https://ijnms.com/index.php/ijnms/article/view/152